Project Sixteen

Bone Regeneration from Muscle-Derived Stem Cells

Audience: Researchers & Physicians | Purpose: Journal Figure

This illustration depicts bone regeneration from muscle-derived stem cells (MDSCs) on a BMP2-induced scaffold. MDSCs form focal expansion nests, proliferate, and migrate radially in spoke-like patterns. Central cells develop into trabecular bone, while outer cells form cortical bone, creating the diploic space. The image also highlights angiogenesis (native tissue invasion) and vasculogenesis (MDSC-formed capillaries connecting with ingrowing vessels), illustrating the dynamic process of bone formation.